全新rapifleX扩展MALDI前因特征开发QC
Bruker介绍rapifleXTM最高性能MALDI-TOF/TOF质谱仪
rapifleX是当今最先进TOF/TOF系统,从地面重构,以满足今天对深度完整自上而下蛋白特征描述和高性能高通量分光成像的最高需求
With its next-generation TOF/TOF ion optics and smartbeam® 10 kHz proprietary laser technology, the rapifleX system now offers significantly higher speed, better mass resolution and mass accuracy, and a significantly enhanced MS/MS mass range to enable new research and routine applications. Its unprecedented 10 kHz speed and ion source robustness, its wide dynamic range, higher specificity and resolution all contribute to the detailed characterization of biologically and clinically relevant lipids, peptides and proteins, resetting customer MALDI-TOF/TOF expectations for in-depth protein characterization and imaging of tissues, cell cultures, or other applications. Its enhanced ease-of-use, robustness and stability make the rapifleX a game-changer for research and large-scale validation.
博士朱利安DLanger在德国美因河畔法兰克福生物物理学和脑研究MPI学院表示:“在我们高MS2隔离效率、分辨率和质精度高m/z值的实验室中,rapifleXTOF/TOF帮助识别并描述mbrane蛋白综合体新子单元,包括procory呼吸链复合体和抗生药目标。”
rapifleXTOF/TOF完全适合生命科学研究和生物制药实验室的详细蛋白特征描述,许多蛋白特征描述任务可以改进以获取更好的生物洞察力,包括生物洞察力
- 快速识别翻译后修改
- 自上而下蛋白排序
- 专利T3序列识别或确认疑似修改或序列转换近蛋白N-或C-termini
- 自动解冻分析完整蛋白而不先验假设使用Bruker独有解冻检测TM法和软件
- 分解分解和分解分析简单化、速度化和动态范围化
组织型和细胞型特定蛋组学是相关生物标志发现和识别的一大进步,需要MLDI成像研究,其中包括识别检测生物标志候选对象验证并随后开发目标测试。rapifleX扩展MALDITissutyr